Insulin requiring Gestational Diabetes: Risk factors and correlation with postpartum diabetes and prediabetes

Objective: A2 gestational diabetes mellitus (A2GDM) is a more severe form of GDM that requires additional medical intervention, such as insulin or oral antidiabetic drug (OAD). The present study explored the determinants A2GDM and analyzed associated risk post-partum prediabetes.
 Methods: This retrospective included 247 pregnant women, diagnosed with followed up until delivery at Obstetric Medicine Clinic King Abdulaziz University Hospital, Jeddah, Saudi Arabia, between January 2014 2018. Women personal history prediabetes were excluded. Collected data patient’s age, body mass index, thyroid dysfunction GDM, HbA1c level diagnosis, management (diet only, insulin, OAD), postpartum metabolic assessment.
 Results: prevalence was 29.6%, which 21.5% insulin-requiring 8.1% OAD-requiring cases. independently positive (OR=3.19, 95% CI = 1.41-7.20) >7% (OR=8.66, 95%CI 2.15- 34.94); model explained 20% variance A2GDM. assessment showed 10.1% have developed prediabetes, while no one overt diabetes. Postpartum predicted by age category ≥45 years (OR=39.94, 4.62-345.06), (OR=0.18, 0.03 – 0.97), (OR=6.96, 1.91-25.42).
 Conclusion: Approximately one-third patients in our institution require OAD for glycemic control are high developing postpartum. Adherence to effectiveness nutrition therapy should be further among improve their both maternal fetal prognosis.
 doi: https://doi.org/10.12669/pjms.39.5.7648
 How cite this: Ghamri KA. Insulin requiring Gestational Diabetes: Risk factors correlation prediabetes. Pak J Med Sci. 2023;39(5):---------. an Open Access article distributed under terms Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), permits unrestricted use, distribution, reproduction any medium, provided original work properly cited.